| 產(chǎn)品編號 | IHC0267H |
| 英文名稱 | Human RalA Ready-To-Use IHC Kit |
| 中文名稱 | 人Ras樣蛋白A即用型免疫組化試劑盒 |
| 別 名 | 3010001O15Rik; AW322615; RAL; Ral-a; RALA; Rasl1; Ral a; Ral A protein; RALA_HUMAN; RAS like protein A; Ras related protein RalA; Ras-related protein Ral-A |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human breast cancer tissue slide using IHC0267H (Human RalA IHC Kit).
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Immunohistochemical analysis of paraffin embedded human colon cancer tissue slide using IHC0267H (Human RalA IHC Kit).
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Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0267H (Human RalA IHC Kit).
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