| 產(chǎn)品編號 |
IHC0274H |
| 英文名稱 |
Human AKT1 Ready-To-Use IHC Kit
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| 中文名稱 |
人蛋白激酶B即用型免疫組化試劑盒 |
| 別 名 |
AKT; AKT1; CWS6; PKB; PKB-ALPHA; PKB/Akt; PKBalpha; PRKBA; RAC; RAC-ALPHA |
| 保存條件 |
Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
AKT1 (PKB alpha) is a serine/threonine kinase that regulates cell survival. The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
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| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human breast cancer tissue slide using IHC0274H (Human AKT1 IHC Kit).
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