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Mouse Integrin alpha 2 Ready-To-Use IHC Kit (IHC0198M)  
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產(chǎn)品編號 IHC0198M
英文名稱 Mouse Integrin alpha 2 Ready-To-Use IHC Kit
中文名稱 小鼠整合素α2(CD49b)即用型免疫組化試劑盒
別    名 CD49B; HPA-5; ITGA2; VLA-2; VLAA2; Integrin alpha 2; CD49b antigen; BR; CD 49b; CD49 antigen like family member B; CD49b; Collagen receptor; DX5; Glycoprotein Ia deficiency included; GP Ia; GP Ia deficiency;included; GPIa; HPA 5 included; HPA5 included; Itga2; Platelet alloantigen Br(a);included; Platelet antigen Br; Platelet glycoprotein GPIa; Platelet glycoprotein Ia; Platelet glycoprotein Ia/Iia; Platelet membrane glycoprotein Ia; Platelet receptor for collagen;deficiency of;included; Very late activation protein 2 receptor alpha 2 subunit; VLA 2 alpha chain; VLA 2; VLA 2 subunit alpha; VLA2 alpha chain; ITA2_HUMAN  
克 隆 號
適用樣品基質 FFPE tissue
保存條件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 CD49b (Integrin alpha 2, Integrin alpha 2 chain, VLA-2 alpha chain, HM alpha 2) is a member of the integrin family. It is a glycoprotein with molecular weight of 150 kD, and it complexes with CD29 (Integrin beta 1) to form the heterodimeric integrin VLA-2 (integrin alpha 2 beta 1, or GPIa/IIa) complex. VLA-2 is an extracellular receptor for laminin, collagen, and fibronectin, and interaction with its ligands results in the activation of intracellular signaling pathways. It has reported roles in VEGF-induced angiogenesis in vivo, as well as adhesion and lymphocyte activation. CD49b is expressed by NK cells, NK-T cells, monocytes, platelets, and epithelial cells. It is also expressed on adaptive immune cells such as T and B cells, specifically on a subset of CD4+ T cells in the spleen, on intraepithelial and lamina propria lymphocytes in the intestine, as well as on a population of peripheral CD4+ type 1 T regulatory (Tr1) cells that co-express LAG-3.

SWISS:
P17301

Gene ID:
3673

產(chǎn)品圖片
Immunohistochemical analysis of paraffin embedded mouse colon tissue slide using IHC0198M (Mouse Integrin alpha 2 IHC Kit).
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