產(chǎn)品編號 | bs-42391P |
英文名稱 | Recombinant human NRF2 protein,N-GST |
中文名稱 | 重組人核因子2相關(guān)因子2蛋白 |
別 名 | Nuclear factor-E2 related factor2; Nrf-2; HEBP1; NF E2 related factor 2; NFE2 related factor 2; NFE2L2; Nrf 2; Nuclear factor erythroid 2 related factor 2; Nuclear factor erythroid derived 2 like 2; NF2L2_HUMAN. |
理論分子量 | 66.5kDa |
性 狀 | Liquid |
濃 度 | >0.5mg/ml |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription
factor which regulates the expression of many detoxification and
antioxidant enzymes. Nrf2 can potentially play a significant role in adaptive responses to oxidative stress. Nrf2 belongs to the Cap N Collar (CNC-bZIP) subfamily of basic /leucine zipper (bZIP) transcription factors. 轉(zhuǎn)錄調(diào)節(jié)因子(Transcriptin Regulators) 核細(xì)胞系因子2相關(guān)因子Nrf2,是一種對氧化還原反應(yīng)敏感的轉(zhuǎn)錄因子,可以通過正向促進(jìn)基因的表達(dá),來轉(zhuǎn)錄翻譯產(chǎn)生一些抗氧化物,行使著異化解毒的酶類和藥物的高效外排泵作用。 有學(xué)者認(rèn)為:核因子2相關(guān)因子2蛋白在保護(hù)細(xì)胞免受環(huán)境毒性物質(zhì)影響方面發(fā)揮著極其重要的作用,它指導(dǎo)某些基因促進(jìn)細(xì)胞的防御工事,同時也刺激某些重要解毒酶對毒性物質(zhì),如黃曲霉素的解毒和排毒作用。 |
產(chǎn)品圖片 | |