產(chǎn)品編號 |
bs-42433P |
英文名稱 |
Recombinant human CHAT protein, N-His
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中文名稱 |
重組人ChAT膽堿乙酰轉(zhuǎn)移酶蛋白 |
別 名 |
Choline O acetyltransferase; Choline O acetyltransferase; Acetyl CoA choline O acetyltransferase; Acetyl CoA:choline O acetyltransferase; ChAT; CHOACTase; Choline acetylase; choline acetyltransferase; CMS1A; CMS1A2; EC 2.3.1.6; OTTHUMP00000019583; OTTHUMP00000019584; CLAT_HUMAN. |
理論分子量 |
42.8kDa |
性 狀 |
Liquid |
濃 度 |
>1mg/ml |
緩 沖 液 |
20mM Tris-Hcl (pH=8.0) with 8M Urea |
保存條件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010].
膽堿乙酰轉(zhuǎn)移酶(Choline Acetyltransferase,ChAT 又稱為:choline O-Acetyltransferase ,CHOACTase;)是催化膽堿和乙酰輔酶A轉(zhuǎn)變?yōu)橐阴:洼o酶A的一種酶。ChAT有M,S,R三個亞型,此抗體與三個亞型都反應(yīng)。
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產(chǎn)品圖片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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