| 產(chǎn)品編號(hào) | bs-42450P |
| 英文名稱 | Recombinant human AQP2 protein |
| 中文名稱 | 重組水通道蛋白-2 |
| 別 名 | ADH water channel; AQP 2; AQP-2; AQP CD; AQPCD; Aquaporin 2 collecting duct; Aquaporin CD; Aquaporin2; Aquaporine 2; Collecting duct water channel protein; MGC34501; Water channel protein for renal collecting duct; WCH CD; WCHCD. |
| 理論分子量 | 35.3kDa |
| 性 狀 | Liquid |
| 濃 度 | >1mg/ml |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant, and recessive forms of nephrogenic diabetes insipidus. Belongs to the MIP/aquaporin (TC 1.A.8) family. 通道蛋白（Channel Protein） 水通道蛋白-2特異地存在于腎臟集合管，受血管加壓素調(diào)節(jié)。有研究證明，AQP2(水通道蛋白-2)在糖尿病腎臟集合管表達(dá)增強(qiáng). 在1型糖尿病動(dòng)物模型的水轉(zhuǎn)運(yùn)中尤其有意義。研究認(rèn)為：AQP-2 奠定了糖尿病大鼠腎臟對(duì)水重吸收的基礎(chǔ)，而且發(fā)現(xiàn)1型糖尿病病人的 AQP-2隨血糖控制而減少。 |
| 產(chǎn)品圖片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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