| 產(chǎn)品編號(hào) | bs-1446R |
| 英文名稱 | TRAP1/HSP75 Rabbit pAb |
| 中文名稱 | 熱休克蛋白75抗體 |
| 別 名 | TRAP1; TRAP-1; Heat shock protein 75; Heat shock protein 75 kDa mitochondrial; HSP 75; HSP 90L; HSP75; HSP90L; TNF receptor associated protein 1; TNFR associated protein 1; TRAP 1; Tumor necrosis factor receptor associated protein; Tumor necrosis factor type 1 receptor associated protein; TRAP1_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Chicken,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 74 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HSP75: 501-650/704 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] Function: Chaperone that expresses an ATPase activity. Subunit: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. Binds to RB1. Subcellular Location: Mitochondrion. Tissue Specificity: Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta. Similarity: Belongs to the heat shock protein 90 family. SWISS: Q12931 Gene ID: 10131 Database links: Entrez Gene: 10131 Human Entrez Gene: 68015 Mouse Entrez Gene: 416666 Chicken Omim: 606219 Human SwissProt: Q12931 Human SwissProt: Q9CQN1 Mouse Unigene: 30345 Human Unigene: 123366 Mouse Unigene: 144695 Rat 信號(hào)傳導(dǎo)（Signaling Intermediates） HSP75/TRAP-1與TNF受體發(fā)生相互作用,可產(chǎn)生促進(jìn)TNF的信號(hào)轉(zhuǎn)導(dǎo)。 |
