| 產(chǎn)品編號 | bs-2057R |
| 英文名稱 | NCX3 Rabbit pAb |
| 中文名稱 | 鈉鈣交換蛋白3抗體 |
| 別 名 | AW742262; MGC90626; Na(+)/Ca(2+)-exchange protein 3; Na+/Ca2+exchange protein 3; Na+/Ca2+exchanger 3; NAC3_HUMAN; NCX3; SCL8A3; Sodium calcium exchanger form 3; Sodium/calcium exchanger 3; Sodium/calcium exchanger SLC8A3; Solute carrier family 8 sodium calcium exchanger member 3. |
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Specific References (1) | bs-2057R has been referenced in 1 publications.
[IF=3.201] Zhang J et al. TRPV4 Complexes With the Na/Ca 2 Exchanger and IP 3 Receptor 1 to Regulate Local Intracellular Calcium and Tracheal Tension in Mice. Front. Physiol., 06 December 2019. Co-IP&WB ; Mouse.
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| 研究領(lǐng)域 | 腫瘤 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 100 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NCX3: 641-740/927 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
SLC8A3 is a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Function: Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity). Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Isoform 2 is expressed in brain and skeletal muscle. Isoform 3 is expressed in excitable cells of brain, retina and skeletal muscle. Isoform 4 is expressed in skeletal muscle. Similarity: Belongs to the sodium/potassium/calcium exchangerv family. SLC8 subfamily. Contains 2 Calx-beta domains. SWISS: P57103 Gene ID: 6547 Database links: Entrez Gene: 6547 Human Entrez Gene: 110893 Mouse Omim: 607991 Human SwissProt: P57103 Human Unigene: 337696 Human Unigene: 443748 Mouse Unigene: 67030 Rat 鈉鈣交換蛋白又稱鈉鈣交換體，有三種同分異構(gòu)體,即NCX1、NCX2和NCX3。3型Na-Ca交換蛋白-NCX3, 主要在腦組織表達(dá)，分布與胞漿及胞膜。 |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Heart tissue lysates
Lane 2: Mouse Kidney tissue lysates
Lane 3: Human U251 cell lysates
Lane 4: Human A549 cell lysates
Primary: Anti-NCX3 (bs-2057R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilu
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