| 產(chǎn)品編號(hào) | bs-1568R |
| 英文名稱 | ENPP3 Rabbit pAb |
| 中文名稱 | ENPP3蛋白抗體 |
| 別 名 | ENPP3; CD203c; ectonucleotide pyrophosphatase/phosphodiesterase 3; RP5-988G15.3; B10; CD203c; NPP3; PD-IBETA; PDNP3; ENPP3_HUMAN. |
| 研究領(lǐng)域 | 免疫學(xué) 通道蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Rat (predicted: Mouse,Pig,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | Flow-Cyt=2μg /test
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 100 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ENPP3: 40-140/875 <Extracellular> |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. Function: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Secreted. Note=Located to the apical surface in intestinal and kidney epithelial cells. Located to the cell surface of basophils, and to the apical plasma membrane of bile duct cells. Secreted in serum, and in lumen of epithelial cells. Tissue Specificity: Expressed in bile ducts, prostate, uterus and colon. Exclusively expressed on basophils, mast cells and their progenitors. Post-translational modifications: N-glycosylation is necessary for correct trafficking to the apical surface, but is not the apical targeting signal. It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both. Similarity: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. Contains 2 SMB (somatomedin-B) domains. SWISS: O14638 Gene ID: 5169 Database links: Entrez Gene: 5169 Human SwissProt: O14638 Human CD203c蛋白是一個(gè)糖基化的2型跨膜蛋白分子,CD203c的表達(dá)主要在嗜堿細(xì)胞、肥大細(xì)胞和它們的前體細(xì)胞上。 |
| 產(chǎn)品圖片 |
Blank control: Raji (blue). Primary Antibody: Rabbit Anti-ENPP3 antibody(bs-1568R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange),used under the same conditions ); Secondary Antibody: Goat anti-rabb
Black line : Positive blank control (Raji); Negative blank control (Molt4）
Green line : Primary Antibody (Rabbit Anti-ENPP3 antibody (bs-1568R) )
Orange line：Isotype Control Antibody (Rabbit IgG) .
Blue line : Secondary Antibody (Goat anti-rabbit IgG-
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