| 產(chǎn)品編號(hào) | bs-1834R |
| 英文名稱 | Rabbit Anti-IL20 antibody |
| 中文名稱 | 白細(xì)胞介素-20抗體 |
| 別 名 | Interleukin-20; four alpha helix cytokine; IL10D; Interleukin 20; Interleukin-20; ZCYTO10; IL20_MOUSE; Cytokine Zcyto10; IL-20; IL20_HUMAN; MGC96907; UNQ852/PRO1801. |
| 研究領(lǐng)域 | 免疫學(xué) 糖蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 17kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse IL-20: 51-150/176 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. Function: Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3. Subcellular Location: Secreted. Tissue Specificity: Expressed at very low levels in skin, trachea, and other tissues. Similarity: Belongs to the IL-10 family. SWISS: Q9JKV9 Gene ID: 58181 Database links: Entrez Gene: 50604 Human Entrez Gene: 58181 Mouse SwissProt: Q9NYY1 Human
SwissProt: Q9JKV9 Mouse 白介素20是新發(fā)現(xiàn)的細(xì)胞因子，屬于白介素10家族成員。它可由活化的外周血單一核細(xì)胞和角質(zhì)形成細(xì)胞產(chǎn)生。與其他白介素10家族成員的受體亞單位有交叉反應(yīng)，多用于銀屑病及風(fēng)濕病的研究。 |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (rat skin tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL-20) Polyclonal Antibody, Unconjugated (bs-1834R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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