| 產(chǎn)品編號 | bs-2690R |
| 英文名稱 | Rabbit Anti-PILRB antibody |
| 中文名稱 | 細(xì)胞表面受體PILRβ抗體 |
| 別 名 | PILRB; Paired immunoglobulin-like type 2 receptor beta; Activating receptor PILR beta; Cell surface receptor FDFACT; Cell surface receptor FDFACT1; Cell surface receptor FDFACT2; FDFACT; FDFACT1; FDFACT2; Paired immunoglobulin like receptor beta; Paired immunoglobulin like type 2 receptor beta; Paired immunoglobulin like type 2 receptor beta precursor; PILRβ. |
| 研究領(lǐng)域 | 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 干細(xì)胞 細(xì)胞膜受體 細(xì)胞表面分子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 23kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PILR beta: 151-227/227 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing. Function: Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface. Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: Q9UKJ0 Gene ID: 29990 Database links: Entrez Gene: 29990 Human Omim: 605342 Human SwissProt: Q9UKJ0 Human Unigene: 632314 Human Ⅱ型成對免疫球蛋白樣受體β蛋白 |
