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Rab24 Rabbit pAb (bs-3868R)  
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50ul/1180.00元
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產品編號 bs-3868R
英文名稱 Rab24 Rabbit pAb
中文名稱 ras基因相關蛋白Rab24抗體
別    名 OTTHUMP00000161435; OTTHUMP00000161437; OTTHUMP00000223588; Rab 24; RAB24; RAB24, member RAS oncogene family; RAB24_HUMAN; Ras related protein Rab 24; Ras-related protein Rab-24.  
研究領域 腫瘤  免疫學  信號轉導  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,Rat (predicted: Human,Rabbit,Pig,Cow,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 23 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Rab24: 1-100/203 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.

Function:
May be involved in autophagy-related processes (By similarity).

Subunit:
Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB. Interacts with ZFYVE20.

Subcellular Location:
Cytoplasm, cytosol. Membrane; Lipid-anchor.

Post-translational modifications:
Isoprenylation is inefficient compared to other Rab family members.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

SWISS:
Q969Q5

Gene ID:
53917

Database links:
UniProtKB/Swiss-Prot: Q969Q5.1

產品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat se
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