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ACSL1 Rabbit pAb (bs-5022R)  
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50ul/1180.00元
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200ul/2800.00元
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產品編號 bs-5022R
英文名稱 ACSL1 Rabbit pAb
中文名稱 長鏈脂肪酸輔酶A連接酶1/2抗體
別    名 ACS 1; ACS1; ACSL 1; Acyl CoA synthetase 1; Acyl CoA synthetase long chain family member 1; FACL 1; FACL 2; FACL1; FACL2; Fatty acid Coenzyme A ligase long chain 1; Fatty acid Coenzyme A ligase long chain 2; LACS 1; LACS 2; LACS; LACS1; LACS2; Lignoceroyl CoA synthase; Long chain acyl CoA synthetase 1; Long chain acyl CoA synthetase 2; Long chain fatty acid CoA ligase 1; Long chain fatty acid CoA ligase 2; Long chain fatty acid coenzyme A ligase 1; Palmitoyl CoA ligase 1; Palmitoyl CoA ligase 2; ACSL1_HUMAN.  
Specific References  (3)     |     bs-5022R has been referenced in 3 publications.
[IF=4.451] Jie Gao. et al. Ferulic acid targets ACSL1 to ameliorate lipid metabolic disorders in db/db mice. J Funct Foods. 2022 Apr;91:105009  IF ;  Mouse,Human.  
[IF=3.86] Chu, Meiqiang, et al. "MicroRNA-126 participates in lipid metabolism in mammary epithelial cells." Molecular and Cellular Endocrinology (2017).  WB ;  Human.  
[IF=1.21] Ma DX et al. CircRNA as CeRNA mediated by microRNA May be Involved in Goat Lactation. Small Ruminant Research.2019 171:63–72  IHF ;  Goat.  
研究領域 腫瘤  細胞生物  免疫學  轉錄調節(jié)因子  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human,Mouse,Pig,Cow,Chicken,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 77 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACSL1: 501-600/698 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. [provided by RefSeq, Jul 2008].

Function:
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.

Subcellular Location:
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein

Tissue Specificity:
Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas.

Similarity:
Belongs to the ATP-dependent AMP-binding enzyme family.

SWISS:
P33121

Gene ID:
2180

Database links:

Entrez Gene: 2180 Human

Entrez Gene: 14081 Mouse

Entrez Gene: 25288 Rat

Omim: 152425 Human

SwissProt: P33121 Human

SwissProt: P41216 Mouse

SwissProt: P18163 Rat

Unigene: 406678 Human

Unigene: 210323 Mouse

Unigene: 6215 Rat



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