| 產(chǎn)品編號 | bs-5909R |
| 英文名稱 | Rabbit Anti-DLL4 antibody |
| 中文名稱 | DeltaD抗體 |
| 別 名 | DeltaD; delta4; delta-like 4 (Drosophila); delta-like 4 homolog (Drosophila); Drosophila Delta homolog 4; delta-like 4 homolog; delta-like 4 protein; Aei; After eight; dld; DLL4_HUMAN; Delta-like protein 4; Drosophila Delta homolog 4; Delta 4 precursor; delta 4; delta ligand 4; notch ligand delta-2; hdelta2; MGC126344; notch ligand DLL4. |
| 研究領(lǐng)域 | 免疫學(xué) 發(fā)育生物學(xué) 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Rat (predicted: Mouse,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 75kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DLL4: 551-650/685 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
DeltaD is one of the 4 members of the zebrafish Delta family of Notch ligands, important in the control of cell differentiation in many tissues.
DeltaD acts as a ligand for Notch receptors and is involved in primary neurogenesis and somitogenesis. It can activate Notch receptors, thereby playing a key role in lateral inhibition, a process that prevents the immediate neighbors of each nascent neural cell from simultaneously embarking on neural differentiation. It is required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized. Function: Cell surface proteoglycan that bears heparan sulfate. Required for cell division patterning during post-embryonic development of the nervous system. Subcellular Location: Cell membrane. Similarity: Belongs to the glypican family. SWISS: Q9NR61 Gene ID: 54567 Database links: Entrez Gene: 54567 Human Entrez Gene: 54485 Mouse Omim: 605185 Human SwissProt: Q9NR61 Human SwissProt: Q9JI71 Mouse Unigene: 511076 Human Unigene: 143719 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human K562 cell Lysates
Lane 2: Human THP-1 cell Lysates
Lane 3: Human 293T cell Lysates
Primary: Anti-DLL4 (bs-5909R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 75kDa
Observed band size: 75kDa
Sample:
Lung (Rat) Lysate at 40 ug
Primary: Anti-DLL4 (bs-5909R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 75 kD
Observed band size: 75 kD
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