產(chǎn)品編號 | bs-5987R |
英文名稱 | Rabbit Anti-ARL11 antibody |
中文名稱 | ADP核糖基化因子樣11抗體 |
別 名 | ADP ribosylation factor like 11; ADP ribosylation factor like protein 11; ADP ribosylation factor like tumor suppressor protein 1; ADP-ribosylation factor-like protein 11; ADP-ribosylation factor-like tumor suppressor protein 1; ARL11; ARL11_HUMAN; ARLTS1. |
Specific References (2) | bs-5987R has been referenced in 2 publications.
[IF=4.46] Alexa Murray. et al. Farnesoid X receptor regulates lung macrophage activation and injury following nitrogen mustard exposure. TOXICOL APPL PHARM. 2022 Aug;:116208 IHC ; Mouse.
[IF=2.145] Sunil VR et al. Sarcoid-Like?Granulomatous?Disease:?Pathologic?Case?Series?in?World?Trade?Center?DustExposed?Rescue?and?Recovery?Workers.Int J Environ Res Public Health. 2019 Mar 6;16(5). IHC-P ; Human.
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研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Pig,Cow) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 21kDa |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ARL11: 65-160/196 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010].
Function: May play a role in apoptosis. May act as a tumor suppressor. Tissue Specificity: Expressed in lung and leukocytes. DISEASE: Defects in ARL11 may be a cause of susceptibility to chronic lymphocytic leukemia (CLL) [MIM:151400]. Similarity: Belongs to the small GTPase superfamily. Arf family. SWISS: Q969Q4 Gene ID: 115761 Database links: UniProtKB/Swiss-Prot: Q969Q4.1 |
產(chǎn)品圖片 |
Tissue/cell: mouse stomach tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-ARL11 Polyclonal Antibody, Unconjugated(bs-5987R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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