| 產(chǎn)品編號(hào) | bs-6507R |
| 英文名稱 | Rabbit Anti-MTCBP1 antibody |
| 中文名稱 | 膜型基質(zhì)金屬蛋白酶胞質(zhì)尾結(jié)合蛋白1抗體 |
| 別 名 | ADI 1; Adi1; Adi-1; ADI1 antibody; APL1; ARD; EC 1.13.; Membrane type 1 matrix metalloproteinase cytoplasmic tail binding protein 1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; MTCBP 1; MTCBP-1; MTCBP1; MTND_HUMAN; Ni-ARD; SIPL; Submergence induced protein 2 homolog; Submergence-induced protein 2 homolog; 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Aci reductone dioxygenase; Acireductone dioxygenase (Ni(2+)-requiring); Acireductone dioxygenase 1 |
| 研究領(lǐng)域 | 腫瘤 信號(hào)轉(zhuǎn)導(dǎo) 腫瘤細(xì)胞生物標(biāo)志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Chicken,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 23kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MTCBP1: 81-126/179 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
his gene encodes an enzyme that belongs to theaci-reductone dioxygenase family of metal-binding enzymes, whichare involved in methionine salvage. This enzyme may regulate mRNAprocessing in the nucleus, and may carry out different functionsdepending on its localization. Related pseudogenes have beendefined on chromosomes 8 and 20. Function: Catalyzes the formation of formate and2-keto-4-methylthiobutyrate (KMTB) from1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Alsodown-regulates cell migration mediated by MMP14. Necessary forhepatitis C virus replication in an otherwise non-permissive cellline. Subunit: Monomer (By similarity). Interacts with MMP14. Subcellular Location: Cytoplasm. Nucleus. Cell membrane;Peripheral membrane protein; Cytoplasmic side. Note=Localizes tothe plasma membrane when complexed to MMP14. Tissue Specificity: Detected in heart, colon, lung, stomach,brain, spleen, liver, skeletal muscle and kidney. Similarity: Belongs to the acireductone dioxygenase (ARD) family. SWISS: Q9BV57 Gene ID: 55256 Database links: Entrez Gene: 55256 Human Entrez Gene: 104923 Mouse NCBI: NP_060739.2 Human Omim: 613400 Human SwissProt: Q9BV57 Human SwissProt: Q99JT9 Mouse Unigene: 502773 Human Unigene: 291504 Mouse Unigene: 12694 Rat |
