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DCTN3 Rabbit pAb (bs-7746R)  
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產(chǎn)品編號 bs-7746R
英文名稱 DCTN3 Rabbit pAb
中文名稱 動力蛋白激活蛋白亞基3抗體
別    名 DCNT22; DCTN 22; DCTN22; Dctn3; DCTN3_HUMAN; dynactin 3(p22); dynactin 3; dynactin 3 isoform 1; Dynactin complex subunit 22 kDa subunit; dynactin light chain; Dynactin subunit 3; p22.  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  細(xì)胞分化  細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human,Rabbit,Pig,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 21 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DCTN3: 41-150/186 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Together with dynein may be involved in spindle assembly and cytokinesis.
Tissue specificity:Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.

Function:
ogether with dynein may be involved in spindle assembly and cytokinesis.

Subunit:
Subunit of dynactin, a multiprotein complex associated with dynein.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Note=Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.

Tissue Specificity:
Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.

Similarity:
Belongs to the dynactin subunit 3 family.

SWISS:
O75935

Gene ID:
11258

Database links:

Entrez Gene: 11258 Human

Entrez Gene: 53598 Mouse

Entrez Gene: 362504 Rat

Omim: 607387 Human

SwissProt: O75935 Human

SwissProt: Q9Z0Y1 Mouse

Unigene: 511768 Human

Unigene: 29025 Mouse

Unigene: 2038 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; An
Paraformaldehyde-fixed, paraffin embedded (Rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; An
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