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fbpB Rabbit pAb (bs-9268R)  
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產品編號 bs-9268R
英文名稱 fbpB Rabbit pAb
中文名稱 結核分枝桿菌Ag85B/fbpB抗體
別    名 A85B_MYCTU; Diacylglycerol acyltransferase/mycolyltransferase Ag85B; Mycobacterium tuberculosis Ag85B; M.tuberculosis Ag85b; EC:2.3.1.122; EC:2.3.1.20; DGAT; 30 kDa extracellular protein; Acyl-CoA:diacylglycerol acyltransferase; Antigen 85 complex B(85B; Ag85B); Extracellular alpha-antigen; Fibronectin-binding protein B(Fbps B); MTCY180.32; Rv1886c;  
Specific References  (2)     |     bs-9268R has been referenced in 2 publications.
[IF=2.738] Liang Wang et al. Clinical Significance of M1/M2 Macrophages and Related Cytokines in Patients with Spinal Tuberculosis. Dis Markers. 2020 May 20;2020:2509454.  IHC ;  Human.  
[IF=1.785] Xiaoqian Shang. et al. Diagnostic value of CXCR3 and its ligands in spinal tuberculosis. Exp Ther Med. 2021 Jan;21(1):1-1  IHC ;  Human.  
研究領域 細胞生物  免疫學  細菌及病毒  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mycobacterium tuberculosis
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 31 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis Ag85B: 231-325/325 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Antigen 85B is the most abundant protein expressed by Mycobacterium tuberculosis (about one quarter). It is a myocolyc transferase in the myc pathway and catalyses - like Ag85A and Ag85C - the transfer of the fatty acid mycolate from one trehalose monomycolate to another, resulting in trehalose dimycolate and free trehalose and helping build the cell wall.

Function:
Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity.

Subcellular Location:
Secreted.

Similarity:
Belongs to the mycobacterial A85 antigen family.

產品圖片
Sample: Lane 1: Recombinant M.tuberculosis fbpB protein Primary: Anti-fbpB (bs-9268R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa
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