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Rabbit Anti-NNP1  antibody (bs-9300R)  
~~~促銷代碼KT202411~~~
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100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-9300R
英文名稱 Rabbit Anti-NNP1  antibody
中文名稱 新型核蛋白質(zhì)1抗體
別    名 NNP 1; NNP-1; NNP1; Nnp1 homolog nucleolar protein; Novel nuclear protein 1; Nucleolar protein Nop52; Protein NNP 1; Protein NNP1; Ribosomal RNA processing 1 homolog; Ribosomal RNA processing protein 1 homolog A; rrp1; RRP1 like protein; RRP1-like protein; RRP1_HUMAN; RRP1A.  
研究領(lǐng)域 細胞生物  細胞周期蛋白  細胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit)
產(chǎn)品應(yīng)用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NNP1/RRP1 like protein: 261-360/461 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Novel nuclear protein 1 (NNP-1), also known as RRP1-like protein or Nucleolar protein Nop52, is a 461 amino acid protein belonging to the RRP1 family. Localized to the nucleolus, NNP-1 has simian virus 40-type and bipartite nuclear localization signals and four coiled-coil domains within its C-terminal region. NNP-1 has been found to play an important role in the generation of 28S rRNA in the late processing steps of ribosome biogenesis. At the end of mitosis, nucleolar proteins assemble in a sequential order during the rebuilding of the nucleolus. NNP-1 assembles after Fibrillarin and C23, and simultaneously with B23 and POP1 in the prenucleolar body pathway.

Function:
Plays a critical role in the generation of 28S rRNA.

Subunit:
Interacts with C1QBP.

Subcellular Location:
Nucleus, nucleolus.

Tissue Specificity:
Ubiquitously expressed in fetal and adult tissues.

Similarity:
Belongs to the RRP1 family.

SWISS:
Q14684

Gene ID:
23076

Database links:

Entrez Gene: 23076 Human

Entrez Gene: 72462 Mouse

Entrez Gene: 309673 Rat

Omim: 610654 Human

SwissProt: Q14684 Human

SwissProt: Q91YK2 Mouse

Unigene: 654727 Human

Unigene: 54275 Rat



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