| 產(chǎn)品編號(hào) | bs-8538R |
| 英文名稱 | Rabbit Anti-EP4 antibody |
| 中文名稱 | 前列腺素E受體蛋白4抗體 |
| 別 名 | Prostaglandin E Receptor EP4; EP 4; EP4; EP-4; EP4R; MGC126583; PE2R4_HUMAN; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostaglandin E receptor 4; Prostaglandin E receptor 4 subtype EP4; Prostaglandin E2 receptor; Prostaglandin E2 receptor EP4 subtype; Prostanoid EP4 receptor; PTGER 2; PTGER 4; PTGER2; PTGER4. |
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Specific References (8) | bs-8538R has been referenced in 8 publications.
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| 研究領(lǐng)域 | 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse (predicted: Rat,Bee) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 53kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EP4R/Prostaglandin E Receptor EP4: 151-250/488 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. Function: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. Subunit: Interacts with FEM1A. Subcellular Location: Cell membrane. Tissue Specificity: High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle. Post-translational modifications: Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P35408 Gene ID: 5734 Database links: Entrez Gene: 5734 Human Entrez Gene: 19219 Mouse Entrez Gene: 443222 Sheep Omim: 601586 Human SwissProt: P35408 Human SwissProt: P32240 Mouse Unigene: 199248 Human Unigene: 18509 Mouse Unigene: 16062 Rat |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Uterus tissue lysates
Lane 2: Mouse Small intestine tissue lysates
Lane 3: Mouse Kidney tissue lysates
Lane 4: Mouse Prostate tissue lysates
Primary: Anti-EP4 (bs-8538R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 55 kD
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