| 產(chǎn)品編號 | bs-11639R |
| 英文名稱 | Rabbit Anti-APPBP2 antibody |
| 中文名稱 | β淀粉樣蛋白前體蛋白結(jié)合蛋白2抗體 |
| 別 名 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN; APP BP2; APP-BP2; Appbp2; PAT1; Ara67 Protein interacting with APP tail 1. |
| 研究領(lǐng)域 | 免疫學(xué) 神經(jīng)生物學(xué) Alzheimer's |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Zebrafish,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 67kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human APPBP2: 201-300/585 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008]. Function: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface. Subunit: Binds APP. Subcellular Location: Nucleus. Cytoplasm Post-translational modifications: Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP. Similarity: Contains 8 TPR repeats. SWISS: Q92624 Gene ID: 10513 Database links: Entrez Gene: 10513 Human Entrez Gene: 66884 Mouse Entrez Gene: 417645 Chicken Omim: 605324 Human SwissProt: Q92624Human SwissProt: Q9DAX9 Mouse Unigene: 84084 Human Unigene: 271997 Mouse Unigene: 104856 Rat |
