| 產(chǎn)品編號 | bs-13233R |
| 英文名稱 | Rabbit Anti-FVT1 antibody |
| 中文名稱 | 濾泡型轉(zhuǎn)運(yùn)蛋白1/II型慢性淋巴性白血病抗體 |
| 別 名 | 3 dehydrosphinganine reductase; 3 ketodihydrosphingosine reductase; 3-dehydrosphinganine reductase; 3-ketodihydrosphingosine reductase; DHSR; FLJ36555; FLJ92680; Follicular lymphoma variant translocation 1; Follicular variant translocation protein 1; FVT 1; FVT-1; FVT1; KDS reductase; KDSR; KDSR_HUMAN; SDR35C1; Short chain dehydrogenase/reductase family 35C member 1. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 轉(zhuǎn)運(yùn)蛋白 細(xì)胞類型標(biāo)志物 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 33kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FVT1: 41-140/332 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). Function: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes. DISEASE: Note=A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. SWISS: Q06136 Gene ID: 2531 Database links: Entrez Gene: 2531 Human Entrez Gene: 70750 Mouse Omim: 136440 Human SwissProt: Q06136 Human SwissProt: Q6GV12 Mouse |
