| 產(chǎn)品編號(hào) | bs-13245R |
| 英文名稱 | G gamma4 Rabbit pAb |
| 中文名稱 | G蛋白偶聯(lián)受體γ4抗體 |
| 別 名 | GNG4; GNGT4; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-4 subunit; GBG4_HUMAN. |
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Specific References (2) | bs-13245R has been referenced in 2 publications.
[IF=5.5] Liang L et al. Distinguishable Prognostic Signatures of Left-and Right-Sided Colon Cancer: a Study Based on Sequencing Data.Cell Physiol Biochem. 2018;48(2):475-490. IHC ; Human.
[IF=4.375] Liang Liang. et al. GNG4 Promotes Tumor Progression in Colorectal Cancer. J Oncol. 2021;2021:9931984 IHC ; Human.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 新陳代謝 G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 8 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human G gamma4: 9-60/75 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. G gamma4 interacts with beta-1 and beta-2, but not with beta-3. It is expressed in brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle. Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Subunit: G proteins are composed of 3 units, alpha, beta and gamma. Interacts with beta-1 and beta-2, but not with beta-3. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Tissue Specificity: Brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle. Similarity: Belongs to the G protein gamma family. SWISS: P50150 Gene ID: 2786 Database links: Entrez Gene: 2786 Human Entrez Gene: 14706 Mouse Omim: 604388 Human SwissProt: P50150 Human SwissProt: P50153 Mouse |
