mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線(xiàn):400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲欧美一区二区三区国产精品,日韩在线视频不卡视频,男女av一区二区三区
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-phospho-IFNAR1 (Tyr466)  antibody (bs-15522R)  
~~~促銷(xiāo)代碼KT202411~~~
訂購(gòu)熱線(xiàn):400-901-9800
訂購(gòu)郵箱:sales@www.p2b3.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@www.p2b3.cn
說(shuō)明書(shū): 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-15522R
英文名稱(chēng) Rabbit Anti-phospho-IFNAR1 (Tyr466)  antibody
中文名稱(chēng) 磷酸化干擾素alpha/beta 受體1蛋白抗體
別    名 IFNAR1 (phospho Y466); p-IFNAR1 (phospho Y466); Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1; IFNAR; IFNAR 1; IFRC; Interferon alpha/beta receptor alpha chain; INAR1_HUMAN.  
研究領(lǐng)域 染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞因子  表觀(guān)遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human,Pig,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 61kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human IFNAR1 around the phosphorylation site of Tyr466 : IN(p-Y)VF 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 IFNAR1 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.

Function:
Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.

Subunit:
Heterodimer with IFNAR2; in presence of interferon alpha and beta ligands, the heterodimer forms the type I interferon receptor. Interacts with STAT1 and STAT2; the interaction requires its phosphorylation at Tyr-466. Interacts with IFNAR2.

Subcellular Location:
Isoform 1: Membrane; Single-pass type I membrane protein.

Tissue Specificity:
IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.

Post-translational modifications:
Phosphorylated on tyrosine residues by TYK2 tyrosine kinase.
Palmitoylation at Cys-463 is required for the activation of STAT1 and STAT2.

Similarity:
Belongs to the type II cytokine receptor family.
Contains 3 fibronectin type-III domains.

SWISS:
P17181

Gene ID:
3454

Database links:

Entrez Gene: 3454 Human

Omim: 107450 Human

SwissProt: P17181 Human

Unigene: 529400 Human



版權(quán)所有 2004-2026 www.www.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
昆明市| 宜川县| 石景山区| 会东县| 荆州市| 天峻县| 淮北市| 黎平县| 嘉禾县| 无棣县| 山阴县| 静乐县| 威海市| 伊春市| 自治县| 洪雅县| 兴海县| 利辛县| 万全县| 沾益县| 东乡族自治县| 阿瓦提县| 沂水县| 阿克苏市| 湖州市| 丹凤县| 古交市| 公主岭市| 南川市| 广西| 罗定市| 乡城县| 集贤县| 渝北区| 垫江县| 密山市| 静安区| 恭城| 施秉县| 沁水县| 兴宁市|