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Rabbit Anti-phospho-CEBPE (Thr74)  antibody (bs-13823R)  
~~~促銷(xiāo)代碼KT202411~~~
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產(chǎn)品編號(hào) bs-13823R
英文名稱 Rabbit Anti-phospho-CEBPE (Thr74)  antibody
中文名稱 磷酸化轉(zhuǎn)錄調(diào)節(jié)因子C/EBPε抗體
別    名 CEBPE (phospho T74); p-CEBPE (phospho T74); C/EBP epsilon; CCAAT/enhancer binding protein (C/EBP) epsilon; CCAAT/enhancer binding protein epsilon; CCAAT/enhancer-binding protein epsilon; CEBPE; CEBPE_HUMAN; CRP 1; CRP1.  
產(chǎn)品類(lèi)型 磷酸化抗體 
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 31kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human CEBPE around the phosphorylation site of Thr74.: PG(p-T)P 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

Function:
C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.

Subcellular Location:
Nucleus.

Tissue Specificity:
Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines.

Post-translational modifications:
Phosphorylated.

SWISS:
Q15744

Gene ID:
1053

Database links:

Entrez Gene: 1053 Human

Entrez Gene: 110794 Mouse

Entrez Gene: 25410 Rat

Omim: 600749 Human

SwissProt: Q15744 Human

SwissProt: Q6PZD9 Mouse

SwissProt: P56261 Rat

Unigene: 558308 Human

Unigene: 236223 Mouse

Unigene: 44462 Rat



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