| 產(chǎn)品編號(hào) | bs-10563R |
| 英文名稱 | Rabbit Anti-ARPC1B antibody |
| 中文名稱 | 肌動(dòng)蛋白相關(guān)蛋白2/3復(fù)合亞單位B1抗體 |
| 別 名 | ARC1B_HUMAN; Actin-related protein 2/3 complex subunit 1B; ARC41; Arp2/3 complex 41 kDa subunit; p41-ARC; actin related protein 2/3 complex subunit 1B; IMD71; PLTEID; p40-ARC; |
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Specific References (1) | bs-10563R has been referenced in 1 publications.
[IF=3.698] Weimin Ni. et al. Actin Related Protein 2/3 Complex Subunit 1 up-regulation in the hypothalamus prevents high-fat diet induced obesity. EUR J NEUROSCI. 2022 Nov;: IF ; Mouse.
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| 研究領(lǐng)域 | 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 41kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ARPC1B: 101-200/372 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011] Function: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Subunit: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Subcellular Location: Cytoplasm, cytoskeleton. Similarity: Belongs to the WD repeat ARPC1 family. Contains 6 WD repeats. SWISS: O15143 Gene ID: 10095 Database links: Entrez Gene: 10095 Human Entrez Gene: 11867 Mouse Omim: 604223 Human SwissProt: O15143 Human SwissProt: Q9WV32 Mouse Unigene: 489284 Human Unigene: 30010 Mouse |
