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Rabbit Anti-CHADL  antibody (bs-13885R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-13885R
英文名稱 Rabbit Anti-CHADL  antibody
中文名稱 軟骨蛋白樣蛋白抗體
別    名 AY100452; CHADL; CHADL_HUMAN; Chondroadherin-like protein; D930017K21Rik; mCG_8786; RP4-756G23.1; SLRR4B.  
研究領域 細胞生物  信號轉導  細胞骨架  細胞外基質  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 79kDa
細胞定位 細胞外基質 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CHADL: 101-200/762 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Members of the small leucine-rich proteoglycan (SLRP) family are mostly extracellular proteins that function upstream of multiple signaling cascades. They affect intracellular phosphorylation and modulate distinct pathways, such as those driven by Toll-like receptors, TGF∫ and receptor tyrosine kinases. As a member of the SLRP family, CHADL (Chondroadherin-like protein) is a 762 amino acid protein containing 21 LRR (leucine-rich) repeats, which promote protein-ligand interactions. Chondroadherin, a closely related protein, promotes attachment of chrondocytes, osteoblasts and fibroblasts and also plays an important role in the regulation of chrodrocyte proliferation and growth. CHADL is a secreted protein that is located in the extracellular space. There are two isoforms of CHADL that exist as a result of alternative splicing events.

Subcellular Location:
Secreted; extracellular space; extracellular matrix.

Similarity:
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily.
Contains 19 LRR (leucine-rich) repeats.
Contains 2 LRRCT domains.
Contains 2 LRRNT domains.

SWISS:
Q6NUI6

Gene ID:
150356

Database links:

Entrez Gene: 150356 Human

SwissProt: Q6NUI6 Human

Unigene: 344488 Human



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