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COQ3 Rabbit pAb (bs-13985R)  
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50ul/1180.00元
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產品編號 bs-13985R
英文名稱 COQ3 Rabbit pAb
中文名稱 線粒體COQ3抗體
別    名 3 4 dihydroxy 5 hexaprenylbenzoate methyltransferase; bA9819.1; Coenzyme Q3 homolog methyltransferase(S. cerevisiae); Coenzyme Q3 homolog methyltransferase(yeast); Coenzyme Q3 homolog methyltransferase; COQ 3; DHHB methyltransferase; DHHB MT; DHHB MTase; DHHBMT; DHHBMTASE; Dihydroxyhexaprenylbenzoate methyltransferase; Hexaprenyldihydroxybenzoate methyltransferase; Hexaprenyldihydroxybenzoate methyltransferase mitochondrial; Methyltransferase COQ3; OTTHUMP00000016892; UG0215E05.  
研究領域 細胞生物  信號轉導  細胞類型標志物  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 41 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human COQ3: 151-250/369 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008]

Function:
COQ3 (Coenzyme Q3 homolog, methyltransferase) is an O-methyltransferase essential in the biosynthetic pathway of coenzyme Q (ubiquinone).

Subcellular Location:
Mitochondrion matrix.

Similarity:
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.

SWISS:
Q9NZJ6

Gene ID:
51805

Database links:

Entrez Gene: 51805 Human

Omim: 605196 Human

SwissProt: Q9NZJ6 Human



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