產(chǎn)品編號 | bs-10593R |
英文名稱 | Rabbit Anti-TRH antibody |
中文名稱 | 促甲狀腺素釋放激素抗體 |
別 名 | Pro-thyrotropin-releasing hormone; Pro-TRH; Prothyroliberin; Thyrotropin-releasing hormone; TRH; Protirelin; TSH-releasing factor; Thyroliberin; Thyrotropin-releasing factor; TRF; TRH_HUMAN. |
研究領(lǐng)域 | 腫瘤 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 生長因子和激素 內(nèi)分泌病 新陳代謝 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 24kDa |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide TRH (pGlu-His-Pro-Amide): 101-200/242 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]. (L-Pyroglutamyl-L-histidyl-L-prolinamide)pGlu-His-Pro Amide, C18H26N6O6 Function: Thyrotropin releasing hormone (TRH) is a tripeptide hormone that stimulates the release of thyroid stimulating hormone and prolactin by the anterior pituitary. TRH is produced by the hypothalamus and travels across the median eminence to the pituitary via the hypophyseal portal system. In addition to the brain, TRH can also be detected in other areas of the body including the gastrointestinal system and pancreatic islets. Subcellular Location: Secreted. Tissue Specificity: Hypothalamus. Expressed in the hair follicle epithelium (at protein level). Similarity: Belongs to the TRH family. SWISS: P20396 Gene ID: 7200 Database links: Entrez Gene: 7200 Human Entrez Gene: 22044 Mouse Omim: 275120 Human SwissProt: P20396 Human SwissProt: Q62361 Mouse Unigene: 1363 Mouse Unigene: 22 Rat |