| 產(chǎn)品編號 | bs-14531R |
| 英文名稱 | Rabbit Anti-EIF1AD antibody |
| 中文名稱 | EIF1AD蛋白抗體 |
| 別 名 | EIF1A_HUMAN; EIF1AD; Eukaryotic translation initiation factor 1A domain containing; Eukaryotic translation initiation factor 1A domain containing protein; Eukaryotic translation initiation factor 1A domain-containing protein; Haponin; Probable RNA binding protein EIF1AD; Probable RNA-binding protein EIF1AD. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)運蛋白 新陳代謝 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Horse,Cynomolgus Monkey) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 19kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EIF1AD: 51-140/165 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
eIF1AD is a 165 amino acid protein that belongs to the eIF1AD family and contains one S1-like domain. eIF1AD localizes to nucleus and is expressed in the glioblastoma cell line U-87 MG, the embryonic kidney cell line HEK-293, the pancreatic carcinoma cell line PANC-1, the breast carcinoma cell line MCF7, the lung cancer cell line NCI-H460, and the chronic myelogenous leukemia cell line K-562. eIF1AD interacts with GAPDH and may function to reduce cell proliferation. The gene encoding eIF1AD maps to human chromosome 11q13.1. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in chromosome 11. Function: Plays a role into cellular response to oxidative stress. Decreases cell proliferation. Subunit: Interacts with GAPDH and STAT1. Subcellular Location: Nucleus. Tissue Specificity: Expressed in the glioblastoma cell line U-87MG, the embryonic kidney cell line HEK-293, the pancreatic carcinoma cell line PANC-1, the breast carcinoma cell line MCF-7, the lung cancer cell line NCI-H460, and the chronic myelogenous leukemia cell line K-562. Similarity: Belongs to the EIF1AD family. Contains 1 S1-like domain. SWISS: Q8N9N8 Gene ID: 84285 Database links: Entrez Gene: 84285 Human Entrez Gene: 69860 Mouse SwissProt: Q4R354 Cynomolgus Monkey SwissProt: Q8N9N8 Human SwissProt: Q3THJ3 Mouse Unigene: 425178 Human Unigene: 299167 Mouse Unigene: 4163 Rat |
