產(chǎn)品編號 | bs-14616R |
英文名稱 | Rabbit Anti-EPS8L1 antibody |
中文名稱 | EPS8L1蛋白抗體 |
別 名 | DRC 3; DRC3; Epidermal growth factor receptor kinase substrate 8 like protein 1; Epidermal growth factor receptor kinase substrate 8-like protein 1; Epidermal growth factor receptor pathway substrate 8 related protein 1; Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8 like 1; EPS8 like protein 1; EPS8-like protein 1; EPS8-related protein 1; EPS8L 1; EPS8L 1; Eps8l1; EPS8R1; ES8L1; ES8L1_HUMAN; FLJ20258; MGC23164; MGC4642; PP10566; PP10566. |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 生長因子和激素 細(xì)胞骨架 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Dog,GuineaPig) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 80kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human EPS8L1: 1-100/723 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Subunit: Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin. Subcellular Location: Cytoplasm. Tissue Specificity: Detected in placenta. Similarity: Belongs to the EPS8 family. Contains 1 SH3 domain. SWISS: Q8TE68 Gene ID: 54869 Database links: Entrez Gene: 54869 Human Entrez Gene: 67425 Mouse Omim: 614987 Human SwissProt: Q8TE68 Human SwissProt: Q8R5F8 Mouse Unigene: 438862 Human Unigene: 360392 Mouse Unigene: 138370 Rat |