| 產(chǎn)品編號 | bs-16105R |
| 英文名稱 | Rabbit Anti-TTC30A antibody |
| 中文名稱 | TTC30A蛋白抗體 |
| 別 名 | FLJ13946; TT30A_HUMAN; Tetratricopeptide repeat domain 30A; TPR repeat protein 30A; TT30A; TTC30A. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞粘附分子 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 76kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TTC30A: 551-665/665 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC30A (tetratricopeptide repeat domain 30A) and TTC30B (tetratricopeptide repeat domain 30B) are cell projection proteins that belong to the TTC30/dfy-1/fleer family. TTC30A and TTC30B contain eight TPR repeats and may be required for polyglutamylation of axonemal tubulin. Both TTC30A and TTC30B may be involved in anterograde intraflagellar transport (IFT), which is a process where cilia precursors are transported from the base of the cilium to the site of incorporation at the tip. TTC30A and TTC30B consists of 665 amino acids and are encoded by a gene located on human chromosome 2q31.2. Function: FLJ13946 is required for polyglutamylation of axonemal tubulin and plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip. Subcellular Location: Cell projection, cilium Similarity: Belongs to the TTC30/dfy-1/fleer family. Contains 8 TPR repeats. SWISS: Q86WT1 Gene ID: 92104 Database links: Entrez Gene: 92104 Human SwissProt: Q86WT1 Human |
