| 產(chǎn)品編號 | bs-16309R |
| 英文名稱 | Rabbit Anti-GRAMD4 antibody |
| 中文名稱 | GRAMD4蛋白抗體 |
| 別 名 | Death-inducing protein; GRAM domain-containing protein 4; GRAM4_HUMAN; GRAMD4. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞凋亡 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 66kDa |
| 細(xì)胞定位 | 細(xì)胞漿 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GRAMD4: 1-100/578 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
GRAMD4 is a mitochondrial effector of E2F1 (MIM 189971)-induced apoptosis (Stanelle et al., 2005 [PubMed 15565177]).[supplied by OMIM, Jan 2011] Function: Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Subcellular Location: Mitochondrion membrane. Colocalizes with COX4I1. Tissue Specificity: Expressed in lung and in primary lung squamous cell carcinoma (LSCC). Similarity: Contains 1 GRAM domain. SWISS: Q6IC98 Gene ID: 23151 Database links: Entrez Gene: 23151 Human Omim: 613691 Human SwissProt: Q6IC98 Human Unigene: 475150 Human |
