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ZNT6 Rabbit pAb (bs-16414R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16414R
英文名稱 ZNT6 Rabbit pAb
中文名稱 ZNT6蛋白抗體
別    名 FLJ31101; MSTP103; SLC30A6; Solute carrier family 30(zinc transporter), member 4; Solute carrier family 30(zinc transporter), member 6; Solute carrier family 30 member 6; Zinc transporter 6; Zinc transporter like 3; ZnT-6; ZnT6; ZNT6_HUMAN.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 51 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNT6: 301-400/461 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A6, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008]

Function:
Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.

Subcellular Location:
Golgi apparatus > trans-Golgi network membrane. Found in vesicules.

Tissue Specificity:
Expressed in brain; especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis.

Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4)
family. SLC30A subfamily.

SWISS:
Q6NXT4

Gene ID:
55676

Database links:

Entrez Gene: 55676 Human

Entrez Gene: 210148 Mouse

Omim: 611148 Human

SwissProt: Q6NXT4 Human

SwissProt: Q8BJM5 Mouse

Unigene: 23248 Human

Unigene: 243943 Mouse



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