產(chǎn)品編號 | bs-16587R |
英文名稱 | Rabbit Anti-TRAPPC6A antibody |
中文名稱 | TRAPPC6A蛋白抗體 |
別 名 | 1810073E21Rik; 4930519D19Rik; AI480686; HSPC289; MGC117907; mhyp; OTTMUSP00000025165; OTTMUSP00000025166; rCG_54352; RGD1309160; TPC6A_HUMAN; Trafficking protein particle complex 6A; Trafficking protein particle complex subunit 6A; TRAPP complex subunit 6A; TRAPPC6A; TRS33. |
Specific References (1) | bs-16587R has been referenced in 1 publications.
[IF=3.687] Yuan FH et al. microRNA‐30a inhibits the liver cell proliferation and promotes cell apoptosis through the JAK/STAT signaling pathway by targeting SOCS‐1 in rats with sepsis. J Cell Physiol. 2019 Apr 10. WB ; Rat.
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研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)運蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 18kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TRAPPC6A: 21-100/159 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
TRAPPC6A is a 159 amino acid protein that localizes to the Golgi apparatus and endoplasmic reticulum. Belonging to the TRAPP small subunits family and the BET3 subfamily, TRAPPC6A may play a role in vesicular transport during the biogenesis of melanosomes. TRAPPC6A is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor. TRAPPC6A exists as a heterodimer with TRAPPC3 and undergoes alternative splicing to produce two isoforms. TRAPPC6A is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a variety of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs). Function: May play a role in vesicular transport during the biogenesis of melanosomes. Subunit: Part of the multisubunit TRAPP (transport protein particle) complex. Heterodimer with TRAPPC3. The heterodimer TRAPPC3-TRAPPC6A interacts with TRAPPC2L. Interacts with TRAPPC2L. Subcellular Location: Golgi apparatus; cis-Golgi network. Endoplasmic reticulum. Similarity: Belongs to the TRAPP small subunits family. BET3 subfamily. SWISS: O75865 Gene ID: 79090 Database links: Entrez Gene: 79090 Human Omim: 610396 Human SwissProt: O75865 Human Unigene: 466929 Human |