產(chǎn)品編號(hào) | bs-16819R |
英文名稱 | Rabbit Anti-KRT24 antibody |
中文名稱 | 細(xì)胞角蛋白24抗體 |
別 名 | CK 24; CK24; Cytokeratin 24; FLJ20261; K24; KA24; K1C24_HUMAN; Keratin 24; Keratin, type I cytoskeletal 24; KRT24; MGC138169; MGC138173; Type I keratin 24. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞骨架 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 55kDa |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞外基質(zhì) 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KRT24: 101-200/525 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jun 2009] Function: KRT24 is a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, comprise the cytoskeleton of epithelial cells. KRT24 is highly expressed in keratinocytes, placenta, colon and spleen, and has been found to be up-regulated in the mucosa of patients suffering of colorectal cancer. Subcellular Location: Intermediate filament; keratin Similarity: Belongs to the intermediate filament family. SWISS: Q2M2I5 Gene ID: 192666 Database links: Entrez Gene: 192666 Human Entrez Gene: 75706 Mouse Omim: 607742 Human SwissProt: Q2M2I5 Human SwissProt: A1L317 Mouse Unigene: 87383 Human |