| 產(chǎn)品編號(hào) | bs-17045R |
| 英文名稱 | Rabbit Anti-phospho-KIF20A (Ser528) antibody |
| 中文名稱 | 磷酸化有絲分裂驅(qū)動(dòng)蛋白樣2抗體 |
| 別 名 | KI20A_HUMAN; Kinesin-like protein KIF20A; MKLP2; RAB6KIFL; RCM6; GG10_2; Mitotic kinesin-like protein 2 (MKlp2); Rab6-interacting kinesin-like protein; Rabkinesin-6; kinesin family member 20A; |
| 產(chǎn)品類型 | 磷酸化抗體 |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 100kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthesised phosphopeptide derived from human KIF20A around the phosphorylation site of Ser528: EH(p-S)LQ |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Enables protein kinase binding activity. Involved in microtubule bundle formation; midbody abscission; and regulation of cytokinesis. Located in several cellular components, including cleavage furrow; intercellular bridge; and midbody. Implicated in restrictive cardiomyopathy. [provided by Alliance of Genome Resources, Apr 2022] Function: Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. Subcellular Location: Golgi apparatus. Cytoplasm > cytoskeleton > spindle. Post-translational modifications: Phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle. Similarity: Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. SWISS: O95235 Gene ID: 10112 Database links: Entrez Gene: 10112 Human Entrez Gene: 19348 Mouse SwissProt: O95235 Human SwissProt: P97329 Mouse |
