| 產(chǎn)品編號 | bs-17068R |
| 英文名稱 | Rabbit Anti-Kir2.2 antibody |
| 中文名稱 | 鉀離子通道Kir2.2抗體 |
| 別 名 | ATP sensitive inward rectifier potassium channel 12; ATP-sensitive inward rectifier potassium channel 12; hIRK; Human high conductance inward rectifier potassium channel alpha; Inward rectifier K; Inward rectifier K(+) channel Kir2.2; Inward rectifier K(+) channel Kir2.2v; inwardly rectifying subfamily J member 12; IRK-2; IRK12_HUMAN; IRK2; KCNJ12; kcnj12x; KCNJN1; Kir2.2v; Potassium channel; Potassium channel inwardly rectifying subfamily J member 12; Potassium inwardly rectifying channel subfamily J member 12; Potassium inwardly rectifying channel,subfamily J inhibitor 1. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞膜受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse,Rat (predicted: Human) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 49kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Kir2.2: 351-433/433 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. Subcellular Location: Membrane. Similarity: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily. SWISS: Q14500 Gene ID: 3768 Database links: Entrez Gene: 100131509 Human Entrez Gene: 100290070 Human Entrez Gene: 3768 Human Entrez Gene: 16515 Mouse Omim: 602323 Human SwissProt: Q14500 Human SwissProt: P52187 Mouse Unigene: 200629 Human Unigene: 4970 Mouse Unigene: 10406 Rat |
