產(chǎn)品編號(hào) | bs-17781R |
英文名稱 | Rabbit Anti-MRPL22 antibody |
中文名稱 | 線粒體核糖體蛋白L22抗體 |
別 名 | 39S ribosomal protein L21; 39S ribosomal protein L21, mitochondrial; 39S ribosomal protein L21, mitochondrial precursor; L21mt; MGC62013; mitochondrial; Mitochondrial ribosomal protein L21; MRP L21; MRP-L21; Mrpl21; RM21_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 線粒體 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Zebrafish,Chicken) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 23kDa |
細(xì)胞定位 | 細(xì)胞漿 線粒體 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MRPL22: 41-120/206 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Subcellular Location: Mitochondrion. Similarity: Belongs to the ribosomal protein L22P family. SWISS: Q9NWU5 Gene ID: 29093 Database links: Entrez Gene: 29093 Human Entrez Gene: 216767 Mouse Omim: 611835 Human SwissProt: Q9NWU5 Human SwissProt: Q8BU88 Mouse Unigene: 483924 Human Unigene: 259907 Mouse Unigene: 13421 Rat |
產(chǎn)品圖片 | |