| 產(chǎn)品編號 | bs-17816R |
| 英文名稱 | Rabbit Anti-MRPS18B antibody |
| 中文名稱 | 線粒體核糖體蛋白S18B抗體 |
| 別 名 | 28S ribosomal protein S18-2; 28S ribosomal protein S18b; 28S ribosomal protein S18b, mitochondrial; C6orf14; DKFZp564H0223; HSPC 183; HSPC183; mitochondrial; Mitochondrial ribosomal protein S18 2; Mitochondrial ribosomal protein S18B; MRP S18 2; MRP S18 b; MRP S18b; MRP-S18-2; MRP-S18-b; MRPS 18B; MRPS18 2; Mrps18-b; MRPS18B; PTD017; RT18B_HUMAN; S18amt; S18mt-b. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)胞類型標(biāo)志物 線粒體 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Cat,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 29kDa |
| 細(xì)胞定位 | 細(xì)胞漿 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MRPS18B: 41-140/258 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Jul 2008] Subunit: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins. Subcellular Location: Mitochondrion. Similarity: Belongs to the ribosomal protein S18P family. SWISS: Q9Y676 Gene ID: 28973 Database links: Entrez Gene: 28973 Human Omim: 611982 Human SwissProt: Q9Y676 Human Unigene: 655329 Human |
