| 產(chǎn)品編號(hào) | bs-18096R |
| 英文名稱(chēng) | Rabbit Anti-HSZFP36/ZNF823 antibody |
| 中文名稱(chēng) | 鋅指蛋白823抗體 |
| 別 名 | ZFP 36 for a zinc finger protein; Zinc finger protein 823; Zinc finger protein ZFP 36; ZNF823. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 70kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HSZFP36/ZNF823: 101-200/610 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HSZFP36, also known as ZNF823 (zinc finger protein 823) or ZFP36, is a 610 amino acid member of the Krüppel C2H2-type zinc-finger protein family and is thought be involved in transcriptional regulation. Localized to the nucleus, HSZFP36 contains one KRAB domain and 16 C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities. Function: The cDNA sequence of HSZFP36 was generated by the Mammalian Gene Collection (MGC) Program Team. Subcellular Location: Nuclear Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 16 C2H2-type zinc fingers. Contains 1 KRAB domain. SWISS: P16415 Gene ID: 55552 Database links: Entrez Gene: 55552 Human SwissProt: P16415 Human Unigene: 534052 Human Unigene: 389856 Mouse |
