產(chǎn)品編號 | bs-18294R |
英文名稱 | Rabbit Anti-LIPN/Lipase N antibody |
中文名稱 | 脂肪水解酶LIPN抗體 |
別 名 | bA186O14.3; LI4; Lipase member N; Lipase, family member N; Lipase-like abhydrolase domain-containing protein 4; LIPL4; Lipn; LIPN_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 新陳代謝 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 44kDa |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LIPN/Lipase N: 101-200/398 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The gene encodes a lipase that is highly expressed in granular keratinocytes in the epidermis, and plays a role in the differentiation of keratinocytes. Mutations in this gene are associated with lamellar ichthyosis type 4. [provided by RefSeq, Dec 2011] Function: Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers. Subcellular Location: Secreted. Tissue Specificity: Exclusively expressed in the epidermis within the granular keratinocytes. Similarity: Belongs to the AB hydrolase superfamily. Lipase family. SWISS: Q5VXI9 Gene ID: 643418 Database links: Entrez Gene: 643418 Human Omim: 613924 Human SwissProt: Q5VXI9 Human Unigene: 632091 Human |