| 產(chǎn)品編號(hào) | bs-18465R |
| 英文名稱 | Rabbit Anti-ZC3H3 antibody |
| 中文名稱 | ZC3H3蛋白抗體 |
| 別 名 | KIAA0150; ZC3H3; ZC3H3_HUMAN; ZC3HDC3; Zinc finger CCCH domain containing protein 3; Zinc finger CCCH domain-containing protein 3; Zinc finger CCCH type containing 3; Zinc finger CCCH type domain containing 3. |
| 研究領(lǐng)域 | 細(xì)胞生物 結(jié)合蛋白 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 103kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZC3H3: 851-948/948 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
ZC3HDC3 is a 948 amino acid protein that contains five C3H1-type zinc finger domains. ZC3HDC3 plays a regulatory role in nuclear adenylation and export. Two isoforms of ZC3H13 exists as a result of alternative splicing events. The gene encoding ZC3H13 maps to chromosome 8, which encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. Similarity: Contains 5 C3H1-type zinc fingers. SWISS: Q8IXZ2 Gene ID: 23144 Database links: Entrez Gene: 23144 Human SwissProt: Q8IXZ2 Human Unigene: 521915 Human |
