| 產(chǎn)品編號 | bs-18492R |
| 英文名稱 | Rabbit Anti-ZNF136 antibody |
| 中文名稱 | 鋅指蛋白136抗體 |
| 別 名 | pHZ 20; Zinc finger protein 136; Zinc finger protein 136 clone pHZ 20; ZN136_HUMAN; ZNF136. |
| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 63kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF136: 451-540/540 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
ZNF136 is a transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family. It is a ubiquitously expressed protein, localizes to the nucleus and contains 14 C2H2-type zinc fingers and 1 KRAB A-domain. Alone, ZNF136 functions as a weak repressor; however, when fused with a heterologous KRAB B-domain containing protein, such as ZNF10, ZNF136 functions as a potent repressor. Function: May be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain. Subcellular Location: Nucleus. Tissue Specificity: Seems ubiquitous. Seen in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 14 C2H2-type zinc fingers. Contains 1 KRAB domain. SWISS: P52737 Gene ID: 7695 Database links: Entrez Gene: 7695 Human Omim: 604078 Human SwissProt: P52737 Human Unigene: 479874 Human |
