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ZHX3 Rabbit pAb (bs-19232R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-19232R
英文名稱 ZHX3 Rabbit pAb
中文名稱 同源三聚體鋅指蛋白ZHX3抗體
別    名 KIAA0395; TIX1; Triple homeobox 1; Triple homeobox protein 1; ZHX 3; Zhx3; ZHX3_HUMAN; Zinc finger and homeodomain protein 3; Zinc fingers and homeoboxes protein 3.  
研究領域 發(fā)育生物學  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Rabbit)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 105 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZHX3: 21-120/956 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. [provided by RefSeq, Jul 2008]

Function:
Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA.

Subcellular Location:
Nucleus.

Tissue Specificity:
Widely expressed. High expression in kidney.

Similarity:
Belongs to the ZHX family.
Contains 2 C2H2-type zinc fingers.
Contains 5 homeobox DNA-binding domains.

SWISS:
Q9H4I2

Gene ID:
23051

Database links:

Entrez Gene: 23051 Human

Omim: 609598 Human

SwissProt: Q9H4I2 Human

Unigene: 380133 Human



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