| 產(chǎn)品編號 | bs-19349R |
| 英文名稱 | Rabbit Anti-NRIP2 antibody |
| 中文名稱 | 核受體相互作用蛋白2抗體 |
| 別 名 | DKFZp761G1913;; Neuronal interacting factor X 1; Nix1; Nrip2; NRIP2_HUMAN; Nuclear receptor interacting protein 2; Nuclear receptor-interacting protein 2. |
| 研究領(lǐng)域 | 細(xì)胞生物 染色質(zhì)和核信號 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 31kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NRIP2: 41-140/281 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
NRIP2 is a 281 amino acid nuclear protein that down-regulates transcriptional activation by nuclear receptors such as ROR∫. The gene encoding NRIP2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders. Function: Down-regulates transcriptional activation by nuclear receptors such as NR1F2. Subunit: Interacts with NR1F2, RARA and THRB in a ligand-dependent manner. Subcellular Location: Nucleus. SWISS: Q9BQI9 Gene ID: 83714 Database links: Entrez Gene: 83714 Human Entrez Gene: 60345 Mouse SwissProt: Q9BQI9 Human SwissProt: Q9JHR9 Mouse Unigene: 530816 Human Unigene: 269883 Mouse |
