| 產(chǎn)品編號(hào) | bs-19603R |
| 英文名稱 | Rabbit Anti-SDHAF1 antibody |
| 中文名稱 | 琥珀酸脫氫酶的組合因子1抗體 |
| 別 名 | LYR motif containing 8; LYR motif-containing protein 8; LYRM8; mitochondrial; SDH assembly factor 1; SDHAF1; SDHF1_HUMAN; Succinate dehydrogenase assembly factor 1; Succinate dehydrogenase assembly factor 1 mitochondrial; Succinate dehydrogenase complex assembly factor 1. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 線粒體 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse (predicted: Rat,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 21kDa |
| 細(xì)胞定位 | 細(xì)胞漿 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SDHAF1: 1-100/115 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits. The protein encoded by this gene resides in the mitochondria, and is essential for SDH assembly, but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency).[provided by RefSeq, Mar 2010] Function: Plays an essential role in succinate dehydrogenase complex (SDH) assembly, a complex involved in complex II of the mitochondrial electron transport chain. Probably acts by participating in mitochondrial biosynthesis of iron-sulfur centers for complex II. Subcellular Location: Mitochondrion matrix. Tissue Specificity: Ubiquitously expressed. DISEASE: Mitochondrial complex II deficiency Similarity: Belongs to the complex I LYR family. SDHAF1 subfamily. SWISS: A6NFY7 Gene ID: 644096 Database links: Entrez Gene: 644096 Human Entrez Gene: 68332 Mouse Omim: 612848 Human SwissProt: A6NFY7 Human SwissProt: Q3U276 Mouse Unigene: 356460 Human Unigene: 6844 Mouse Unigene: 3527 Rat |
| 產(chǎn)品圖片 |
Sample:
Jurkat(Human) Cell Lysate at 30 ug
Primary: Anti-SDHAF1 (bs-19603R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 21 kD
Observed band size: 22 kD
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