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Rabbit Anti-SH3D20  antibody (bs-19753R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-19753R
英文名稱 Rabbit Anti-SH3D20  antibody
中文名稱 SH3結(jié)構(gòu)域結(jié)合蛋白D20抗體
別    名 ARHGAP27; CAMGAP1; CIN85-associated multi-domain-containing Rho GTPase-activating protein 1; PP905; RHG27_HUMAN; Rho GTPase-activating protein 27; Rho-type GTPase-activating protein 27; SH3 domain containing 20; SH3 domain containing protein 20; SH3D20; SH3P20.  
研究領域 腫瘤  細胞生物  信號轉(zhuǎn)導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 98kDa
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SH3D20: 531-630/889 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013]

Function:
Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1.

Subcellular Location:
Cytoplasm. Membrane.

Tissue Specificity:
Expressed in germinal center B-cell, spleen, chronic lymphocytic leukemia, pancreatic cancer and lung cancer.

Similarity:
Contains 1 PH domain.
Contains 1 Rho-GAP domain.
Contains 1 SH3 domain.
Contains 3 WW domains.

SWISS:
Q6ZUM4

Gene ID:
201176

Database links:

Entrez Gene: 201176 Human

Entrez Gene: 544817 Mouse

Entrez Gene: 303583 Rat

Omim: 610591 Human

SwissProt: Q6ZUM4 Human

SwissProt: A2AB59 Mouse

SwissProt: Q6TLK4 Rat

Unigene: 205326 Human

Unigene: 397197 Mouse

Unigene: 17895 Rat



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