| 產(chǎn)品編號(hào) | bs-21147R |
| 英文名稱 | Rabbit Anti-RALGPS1 antibody |
| 中文名稱 | RALGPS1蛋白抗體 |
| 別 名 | Ral GEF with PH domain and SH3 binding motif 1; RalA exchange factor RalGPS1; RALGEF2; RALGPS1A; Ras specific guanine nucleotide releasing factor RalGPS1. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 62kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RALGPS1: 461-557/557 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
May be involved in cytoskeletal organization (By similarity). May also be involved in the stimulation of transcription in a Ras independent fashion (By similarity). Guanine nucleotide exchange factor for the small GTPase RALA. Six different isoforms have been described. Function: Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for. Subunit: Interacts with the SH3 domains of GRB2, NCK1, PLCG1 and SRC. Subcellular Location: Cell Membrane and Cytoplasmic. Tissue Specificity: Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus. SWISS: Q5JS13 Gene ID: 9649 Database links: Entrez Gene: 9649 Human SwissProt: Q5JS13 Human Unigene: 648175 Human |
