| 產(chǎn)品編號(hào) | bs-21942R |
| 英文名稱 | Rabbit Anti-GPR39 antibody |
| 中文名稱 | G蛋白偶聯(lián)受體39抗體 |
| 別 名 | GPCR GPR39; G protein coupled receptor GPR39; G Protein-Coupled Receptor 39; GPR 39; GPR39; GPR-39; MGC149541. |
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Specific References (1) | bs-21942R has been referenced in 1 publications.
[IF=5.652] Panpan Yang. et al. The mechanism underlying the TC-G 1008 rescue of reactive oxygen species (ROS)-induced osteoblast apoptosis by the upregulation of peroxiredoxin 1. INT J BIOCHEM CELL B. 2022 Aug;:106276 WB ; Mouse.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞膜受體 G蛋白偶聯(lián)受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 51kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPR39: 261-360/453 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
GPCR39 is an integral membrane protein, which belongs to family 1 of G-protein coupled receptors. GPCR39 expression has been documented in human brain and peripheral tissues. ESTs have been isolated from human tissue libraries, including normal eye, brain, heart, melanocyte, uterus, vessel, cancerous brain, germ cell, kidney, and ovary. Function: Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death. Subcellular Location: Multi-pass membrane protein Tissue Specificity: Expressed in many tissues, including the stomach, intestine and hypothalamus. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: O43194 Gene ID: 2863 Database links: Entrez Gene: 2863 Human Entrez Gene: 71111 Mouse Omim: 602886 Human SwissProt: O43194 Human SwissProt: Q5U431 Mouse |
| 產(chǎn)品圖片 |
Sample:
A431(Human) Cell Lysate at 30 ug
Primary: Anti-GPR39 (bs-21942R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD
Sample:
Lung (Mouse) Lysate at 40 ug
Primary: Anti- GPR39 (bs-21942R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD
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